Adrenal and hepatic aspergillosis in an immunocompetent patient

Abstract

Invasive aspergillosis, an infection most frequently induced by Aspergillus fumigatus and Aspergillus flavus, typically occurs in immunocompromised patients and is usually transmitted through inhalation of Aspergillus spores. As the lungs are by far the most common site involved in invasive aspergillosis and invasive aspergillosis in immunocompetent hosts is very rare, there have been a few case reports of extra-pulmonary, disseminated invasive aspergillosis in immunocompetent persons. Herein, we report a case of an adult, male, immunocompetent patient with disseminated invasive aspergillosis that successively spread from the right adrenal gland to the left hepatic lobe. The patient was successfully treated through surgical excisions of his adrenal and hepatic masses followed by voriconazole therapy. To our knowledge, this is the first case report of invasive aspergillosis affecting the adrenal glands.

Keywords::

• Aspergillus
• aspergillosis
• adrenal
• liver
• hepatic
• immunocompetent

Ethics

This study was conducted with approval from Ethics Committee (IRB) of West China Hospital, Sichuan University (Chengdu, China). Written informed consent was obtained from the patient (registry no. 0001321074). As ethical and legal considerations require careful attention to the protection of a patient's anonymity in case reports, identifying information such as names, initials, hospital numbers, and dates were redacted.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.