Abstract
Persistence of pneumococcal capsular antigens (PCA) In sputum was studied by counterim-munoelectrophoresis (CIE) in 36 cases of pneumococcal pneumonia. Antigens were still detected 24 and 48 h after start of antimicrobial treatment, in 92% and 76% respectively of the patients with lobar or multilobar Infiltrates. Persistence of PCA was associated with radiologic extension of lung infiltrate. CIE appears to be a valuable diagnostic tool for pneumococcal pneumonia, when treatment has been instituted before admission to the hospital.