Serum IgG and IgA Antibody Responses to Campylobacter pylori in a Group of Healthy Asymptomatic Volunteers

Abstract

Sera from 17 healthy asymptomatic volunteers were tested for presence of IgG and IgA antibodies against Campylobacter pylori and correlated with endoscopic biopsy findings. Three volunteers infected with C. pylori had the highest IgG antibody titers of the group. None of 14 C. pylori free subjects had significant IgG antibody levels. IgA antibody titers were negative in all subjects regardless of state of infection, in contrast to control sera from symptomatic C. pylori infected patients who manifested high IgA antibody levels.