Correlation between macrosomia body indices and maternal fasting blood glucose

Abstract

To explore the significance of neonatal body indices in identifying pathological macrosomia, we implemented a retrospective study of 254 neonates, including: 100 macrosomia of diabetic pregnancies, 77 macrosomia of healthy pregnancies and 77 normal neonates of healthy pregnancies, using their birth weight, body length, head circumference and chest circumference, to calculate neonatal body indices, multiple regression analysis of the correlation between newborn body indices and maternal fasting blood glucose. The Quetelet Index and Kaup Index of diabetic macrosomia is higher than that of non-diabetic macrosomia; HC:CC (ratio between head circumference and chest circumference) is reversed (p < 0.05). The multiple regression equation of neonatal body indices to maternal fasting blood glucose is BG = 6.959 + 0.031 QI –4.482 × HC:CC. Quetelet index and HC:CC have linear relationship with maternal fasting blood glucose (p < 0.05). Compared with birth weight, Quetelet Index and HC:CC could better reflect the effect of maternal metabolism on the fetus and be of great significance in the prediction of fetal macrosomia.

Keywords::

• Gestational diabetes mellitus
• macrosomia
• neonatal body indices

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

WeiWei Song received a research grant from National Natural Science Foundation of China, No. 30672237.