Diagnostic Accuracy of Neutrophil/Lymphocyte Ratio, Red Cell Distribution Width and Platelet Distribution Width in Ovarian Torsion

Abstract

The main aim of this diagnostic case–control study of 136 patients with ovarian cysts (44 patients with ovarian torsion and 92 controls) was to determine the diagnostic value of haematologic inflammatory markers (neutrophil/lymphocyte ratio [NLR], red cell distribution width [RDW] and platelet distribution width [PDW]) for torsioned ovarian cysts. The presence of a torsioned ovarian cyst was identified by a 1.18-fold increase in the NLR (95%CI: 1.04–1.34, P = 0.009), a 1.22-fold increase in the RDW (95%CI: 1.04–1.43, P = 0.023) and a 1.93-fold increase in the PDW (95%CI: 1.19–3.14, P = 0.007). The NLR was the best predictor of a torsioned ovarian cyst (AUC: 0.74; 95% CI: 0.68–0.83). When an NLR cut-off value of 2.44 was used to determine ovarian torsion, the sensitivity, specificity, + LR and –LR were 70.5%, 70.7%, 2.40 and 0.42, respectively. In conclusion, the NLR may have diagnostic and prognostic value in determining torsioned ovarian cysts.

Keywords::

• Torsioned ovarian cyst
• haematologic inflammatory markers
• diagnosis
• neutrophil/lymphocyte ratio
• red cell distribution width
• platelet distribution width

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.