Treatment of Asthenozoospermia by Intratesticular Testosterone Therapy

M. S. Fahim Department of Obstetrics and Gynecology, University of Missouri School of Medicine, Columbia, Missouri

H. H. Ibrahim Departments of Physiology, Andrology, and Gynecology and Obstetrics, University of Cairo, Faculty of Medicine, Cairo, Egypt

S. M. Girgis Departments of Physiology, Andrology, and Gynecology and Obstetrics, University of Cairo, Faculty of Medicine, Cairo, Egypt

M. I. Abdalla Departments of Physiology, Andrology, and Gynecology and Obstetrics, University of Cairo, Faculty of Medicine, Cairo, Egypt

A. A. Awwad Departments of Physiology, Andrology, and Gynecology and Obstetrics, University of Cairo, Faculty of Medicine, Cairo, Egypt

Abstract

A single intratesticular injection of 0.5 cc of 50 mg/ml of an aqueous testosterone suspension was administered to 14 patients with asthenozoospermia. In 7 cases, injection was combined with ultrasound of 0.5 w/cm² for 2 min weekly for 4 weeks. In another 4 cases, only ultrasound was applied. Intratesticular injection with or without ultrasound caused a significant increase of motility percentage. Sperm density improved in cases that were associated with oligozoo-spermia (< 20 million/ml). Ultrasound therapy (0.5 w/cm² for 2 min) used alone had no effect on semen parameters. Associated hormonal changes in blood plasma were evaluated.

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Treatment of Asthenozoospermia by Intratesticular Testosterone Therapy

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