Impaired Dna Synthesis by Early Pubertal Cryptorchid Testis In Vitro

M. Nakamura Department of Urology, Osaka University, Osaka, 553, Japan

N. Nonomura Department of Urology, Osaka University, Osaka, 553, Japan

M. Namiki Department of Urology, Osaka University, Osaka, 553, Japan

A. Okuyama Department of Urology, Osaka University, Osaka, 553, Japan

E. Koh Department of Urology, Osaka Central Hospital, Osaka, 553, Japan

N. Kondoh Department of Urology, Osaka Central Hospital, Osaka, 553, Japan

M. Takeyama Department of Urology, Osaka Central Hospital, Osaka, 553, Japan

H. Fujioka Kinki Central Hospital, Osaka, 553, Japan

H. Kiyohara Department of Urology, Osaka Central Hospital, Osaka, 553, Japan

Y. Nishimune School of Medicine and Research Institute for Microbial Diseases, Osaka University, Osaka, 553, Japan

K. Matsumoto Department of Pathology, Osaka University, Osaka, 553, Japan

M. Matsuda Department of Urology, Osaka University, Osaka, 553, Japan

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Abstract

To study the spermatogenic potential of the early pubertal cryptorchid testis, testicular DNA synthesis was examined in vitro. DNA synthesis by early pubertal cryptorchid testis was inhibited and lost its normal temperature sensitivity. The spermatogenic potential of the cryptorchid testis may be impaired as early as puberty.

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Impaired Dna Synthesis by Early Pubertal Cryptorchid Testis In Vitro

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Impaired Dna Synthesis by Early Pubertal Cryptorchid Testis In Vitro

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