Hypo-Osmotic Sperm Swelling Test Does not Assess Fertilizing Capacity of Human Spermatozoa

S. Jager Section of Reproductive Medicine, Department of Obstetrics and Gynaecology, University Hospital, Groningen, The Netherlands

J. Kremer Section of Reproductive Medicine, Department of Obstetrics and Gynaecology, University Hospital, Groningen, The Netherlands

J. Wuchman Section of Reproductive Medicine, Department of Obstetrics and Gynaecology, University Hospital, Groningen, The Netherlands

Abstract

The hypo-osmotic sperm swelling (HOSS) test was performed on semen samples of five normospermic men from couples with prolonged infertility. Previously, the men had negative results of the zona-free hamster oocyte (ZFHO) test on two different ejaculates and the wives subsequently had become pregnant by donor insemination. A high swelling percentage (at least 60%) was found in all five men. It would appear that the HOSS test does not assess fertilizing capacity.

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Hypo-Osmotic Sperm Swelling Test Does not Assess Fertilizing Capacity of Human Spermatozoa

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Hypo-Osmotic Sperm Swelling Test Does not Assess Fertilizing Capacity of Human Spermatozoa

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