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Case Reports

Langerhans Cell Histiocytosis of the Pituitary Gland Presenting as Unilateral Reversible Central Visual Loss and a Contralateral Junctional Scotoma

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Pages 133-137 | Received 14 Oct 2010, Accepted 13 Jan 2011, Published online: 18 Jun 2011
 

Abstract

A 28-year-old woman developed Langerhans cell histiocytosis involving the hypothalamic-pituitary axis and presented with acute vision loss in the left eye, a junctional scotoma in the right eye, panhypopituitarism, and diabetes insipidus. Following endoscopic transphenoidal excision of the lesion, her vision improved in the affected eye and the junctional scotoma disappeared from the other eye. This is an unusual case of Langerhans cell histiocytosis of the hypothalamic-pituitary axis leading to a reversible anterior chiasmal (junctional) syndrome.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

Note: of this article is available in colour online at www.informahealthcare.com/oph

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