Neuro-Sweet Disease Causing Orbital Inflammation

Abstract

Neuro-Sweet disease is a rare condition causing encephalitis or meningitis in addition to the erythematous skin plaques of Sweet syndrome. Neuro-Sweet disease has been associated with several ocular manifestations, including ocular movement disorders, episcleritis, conjunctivitis, uveitis, and optic disc oedema. The author reports a patient with orbital inflammation, cranial neuropathies, and a skin rash in the setting of myelodysplastic syndrome. Biopsy of her skin lesion confirmed the diagnosis of neuro-Sweet disease. To the author’s knowledge, this is the first reported case of neuro-Sweet disease causing orbital inflammation. Her ocular inflammation resolved with the use of systemic corticosteroid treatment.

• Neuro-Sweet disease
• orbital cellulitis
• orbital inflammation
• Sweet syndrome

Acknowledgement

This work was supported by an unrestricted grant from Research to Prevent Blindness.

Declaration of interest: The author reports no conflicts of interest. The author alone is responsible for the content and writing of the paper.