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The International Journal on Orbital Disorders, Oculoplastic and Lacrimal Surgery
Volume 31, 2012 - Issue 5
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Case Reports

A Case of Orbital Involvement in IgG4-Related Disease

Joshua C. TeichmanDivision of Ophthalmology, McMaster University, Hamilton, Ontario, Canada
, MD, MPH,
Albert Y. Wu
, MD, PhD,
Ihab El-ShinnawyDepartment of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada
, MBBCh, FRCPC, FCAP, FASCP &
John T. HarveyDivision of Ophthalmology, McMaster University, Hamilton, Ontario, CanadaCorrespondence[email protected]
, MD, FRCSC
Pages 327-329 | Received 02 Jun 2011, Accepted 17 Aug 2011, Published online: 19 Jun 2012
 
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Abstract

A 46-year-old male was referred to the Ophthalmology Service for a 7-year history of bilateral proptosis and a presumptive diagnosis of thyroid eye disease. Past medical history was only significant for autoimmune pancreatitis. All laboratory testing including tests of thyroid function were within normal limits. The patient underwent orbital biopsy and was found to have plasma cells containing mainly IgG4 immunoglobulin that was consistent with IgG4-related disease. The patient was treated with oral prednisone and the proptosis resolved within 3 weeks.

Declaration of interest: The authors report no conflicts of interest.

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