Dispersion of Aerosol Particles in an Airway Cast of a Dog

Abstract

Aerosol bolus dispersion was measured in the first branching generations of a replicate hollow cast. The cast was made from a solid cast of a beagle-dog tracheobronchial tree. The dispersion was measured after penetration of boluses into different volumetric depths, with different particle sizes and flow rates into the cast. An enhanced flow rate led to a decreasing dispersion in the cast. Particle size up to about 4 μm has no significant effect on dispersion.

Key Words:

• aerosol inhalation
• aerosol dispersion
• airways
• aerosol probe
• bolus dispersion
• airway cast
• beagle dog