Upper Abdominal Neoplasms: An Introduction and Selected References

Abstract

The organs in the upper half of the abdominal cavity can give rise to a highly heterogeneous collection of neoplasms that encompasses a broad spectrum of clinical features, light microscopic appearances, immunostaining properties, and fine structure. Because of the anatomic proximity of the viscera in this region, the differential diagnosis of an upper abdominal mass may include consideration of tumors that arise from the stomach, duodenum, liver, kidney, adrenal, and pancreas. There are many distinctive ultrastructural features among the various tumors that can be used effectively by the diagnostic electron microscopist, but it is also important to take into account the considerable overlap in fine structure that occurs among different tumors and among similar tumors from different organs. In the session on upper abdominal neoplasms, the electron microscopic characteristics of the common tumors of each viscus were reviewed before the presentation of individual case studies that incorporated original observations and illustrated some unusual entities. The selection of cases that follows is inevitably small and arbitrary, but the cases demonstrate the contribution that electron microscopy can make in the study of an upper abdominal mass and illustrate some of the similarities that can be encountered among tumors of different organs.