Merkel Cell Carcinoma with Pagetoid Spread

Ludvik R. Donner Department of Pathology, Scott and White Clinic, Scott, Sherwood and Brindley Foundation, Texas A & M University School of Medicine, 2401 South 31st Street, TempleTexas, 76508, USA

V. O. Speights Department of Pathology, Scott and White Clinic, Scott, Sherwood and Brindley Foundation, Texas A & M University School of Medicine, 2401 South 31st Street, TempleTexas, 76508, USA

Raymond A. Trompler Department of Pathology, Scott and White Clinic, Scott, Sherwood and Brindley Foundation, Texas A & M University School of Medicine, 2401 South 31st Street, TempleTexas, 76508, USA

Abstract

A case of Merkel cell carcinoma showing epidermo-tropism is presented. The neoplastic cells displayed dotlike immunoreactivity for cytokeratins and strong immunoreactivity for neuron-specific eno-lase. Although no neuroendocrine granules were found, characteristic paranuclear fibrous bodies were present.

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Merkel Cell Carcinoma with Pagetoid Spread

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Merkel Cell Carcinoma with Pagetoid Spread

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