Ribosome-Lamella Complexes in the Perineurial Cells of Neurofibromatosis

Abstract

Ribosome-lamella complexes are occasionally seen in neoplastic disorders of the hematopoietic system, particularly in hairy cell leukemia. However, these structures are rare in epithelial and mesenchymal cells. In this report three tumors from a patient with neuro-fibromatosis (von Recklinghausen's disease) are examined by electron microscopy. Ribosome-lamella complexes were seen in the perineurial cells. This may be the first report of these complexes in nerve sheath tumors.

Key Words:

• electron microscopy
• neurofibromatosis
• perineurial cells
• ribosome-lamella complexes
• von Recklinghausen's disease