Metachronous occurrence of a temporal ganglioglioma and a bifrontal anaplastic ependymoma: Coincidence or an explainable pathological curiosity?

Abstract

In this first-of-its-kind report, we describe an unusual case of a 32-year-old man who harboured two biologically distinct metachronous brain tumours. He presented with features of raised intracranial pressure 8 years after total excision of a right temporal ganglioglioma. Imaging showed a heterogenously contrast enhancing bifrontal lesion with ventricular extension. Histopathological examination revealed an anaplastic ependymoma. While a co-incidental occurrence is a possibility, there could be possible mechanisms to explain this pathological oddity.

Key words:

• Metachronous tumours
• ganglioglioma
• ependymoma

Source of support:

The authors have not received any support, in the form of grant, from any source for preparation of this article. Neither do the authors, nor does the institute have any personal or institutional financial interest in drugs, materials, or devices described in their submissions.

Disclosure:

This paper has not been published before and has not been submitted for publication to any other journal in part or full. It has not been presented in any meeting/conference. The authors concur with this submission and there is no conflict of interest arising from this article. The manuscript has been prepared as per the guidelines laid down by the institutes.

Declaration of interest:

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.