Radiation-induced anaplastic ependymoma with a remarkable clinical response to temozolomide: a case report

Abstract

Radiation-induced gliomas are uncommon and therapeutic options are limited due to prior exposure to radiotherapy. Meanwhile, the chemotherapeutic response of anaplastic ependymoma, another rare entity in adults, is often disappointing. We report on the first recorded case of radiation-induced anaplastic ependymoma, in which an excellent clinical response to temozolomide was demonstrated.

Keywords::

• anaplastic
• ependymoma
• glioma
• radiotherapy
• radiation-induced
• temozolomide

Declaration of interest: The authors report no declarations of interest. The authors alone are responsible for the content and writing of the paper.