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Original Article

Acute predictors for mortality after severe TBI in Spain: Gender differences and clinical data

, , , , , & show all
Pages 1439-1444 | Received 02 Dec 2014, Accepted 07 Jul 2015, Published online: 21 Aug 2015
 

Abstract

Objective: The main objective of this study is to determine whether gender affects global mortality and functional outcome after severe traumatic brain injury (TBI).

Methods: This retrospective cohort study included 629 patients with severe TBI (14.9% female) admitted to the ICU of a university hospital. Patients were split into gender groups to study potential differences in global mortality and functional outcome at ICU discharge and 6 months post-trauma using the GOS. The following variables were analysed: age, intracranial injury, injury mechanism, injury severity, factors contributing to secondary brain injury, monitoring level, treatment, complications, length of stay in the ICU and cause of death.

Results: No differences were found between gender groups in neuromonitoring level or surgical procedures. Women had higher APACHE II scores, a higher incidence of pre-hospital hypotension, anaemia and transfusion and higher mortality rates in the ICU (OR = 1.74; 95% CI = 1.09–2.77) and 6 months post-trauma (OR = 1.65; 95% CI = 1.02–2.67). There were no significant differences in functional outcome at ICU discharge or 6 months post-injury. The multivariate analysis did not show gender as an independent predictive factor in mortality after severe TBI.

Conclusion: In this study, gender was not found to be an independent predictor for poorer outcome after severe TBI.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

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