Comparison between Obtained Mydriasis in Type 2 Diabetics and Non-Diabetic Patients

Abstract

Background/Aims: To evaluate and compare obtained mydriasis with phenylephrine 10% associated with tropicamide 1% in type 2 diabetics and non-diabetic patients.

Methods: A total of 50 patients (100 eyes) scheduled for fundoscopy were dilated with phenylephrine 10% and yropicamide 1% (group 0: n = 20 type 2 diabetic patients, 40 eyes, and group 1: n = 30 non-diabetic patients, 60 eyes). Only one drop per eye of each drug was administered. In both groups, pupil diameter was measured after 40 minutes of eye drops instillation.

Results: Both groups were similar regarding age (p = 0.06, Mann-Whitney test). Mean pupil diameter in group 0 was 8.57 and 8.73 in group 1. There was no statistic difference between both groups (p = 0.44). Pupil diameter was greater than 7 mm in all patients (100%).

Conclusion: When an appropriate drug combination is used, diabetic patients can achieve mydriasis as satisfactory as non-diabetic patients, allowing adequate fundus examination and/or retinopathy treatment.

KEYWORDS::

• Adrenergic drugs
• Diabetes mellitus
• Fundus examination
• Mydriatic drugs
• Pupil diameter

ACKNOWLEDGEMENTS

Declaration of interest: The authors report no conflict of interest. The authors alone are responsible for the content and writing of the paper.