Early diagnosis based on clinical history and BALF for successful management of smoking-induced acute eosinophilic pneumonia without unnecessary antibiotic usage: a case report

Abstract

Introduction: Acute eosinophilic pneumonia (AEP) is a rapid onset and severe respiratory illness characterized by acute febrile respiratory insufficiency, eosinophilic infiltration in the lungs and unique findings on chest imaging. Difficulty in differentiating from other respiratory distress caused by community-acquired pneumonia may result in a delayed diagnosis or treatment with empirical antibiotics. Case study: Sixteen-year-old boy who developed AEP with marked eosinophilia in bronchoalveolar lavage fluid (BALF, 36.6%), decreased diffusion capacity of the lung for carbon monoxide (62%) and unique radiological findings. Although he initially denied tobacco use, on repeated thorough clinical history questioning, he eventually admitted beginning smoking 19 days before the onset of symptoms with gradually increasing frequency. Results: His symptoms resolved quickly without use of antibiotics after cessation of tobacco and treatment with corticosteroids. Conclusion: Careful clinical history taking regarding tobacco use combined with early examination of BALF and recognition of unique radiological findings are critical for proper management of AEP.

• Bronchoalveolar lavage fluid
• child
• medical history taking
• pulmonary eosinophilia
• tobacco smoke pollution.

Acknowledgements

The authors wish to thank him and parents for publication of this case report and any accompanying images. Written informed consent was obtained from the patient and caregiver for publication of this case report and any accompanying images.

Declaration of interest

This work was supported in part by the Soonchunhyang University Research Fund. The authors have nothing to disclose that poses a conflict of interest.