5
Views
9
CrossRef citations to date
0
Altmetric
Original Article

Experimental Laryngeal Reconstruction with Preformed Composite Graft

&
Pages 259-271 | Received 23 Apr 1986, Published online: 08 Jul 2009
 

Abstract

The use of perichondrial grafts for reconstruction of the thyroid cartilage of the larynx was studied in two series of rabbits. In the first pilot study the thyroid cartilage was replaced by a cartilage preformed by the neochon-drogenic effect of an auricular perichondrial graft set into the defect on a subcutaneous flap. When this transplantation technique proved successful, another series was performed where a laryngeal defect of the thyroid cartilage and the underlying mucosa were replaced by a preformed composite graft. This composite graft consisted of a biological support of newly formed cartilage from the neochon-drogenic effect of a free perichondrial graft and mucosal lining made of a retention cyst from a free graft of oral mucosa. The newly formed composite graft was transferred to set into the laryngeal defect on a subcutaneous flap. The reconstruction was successful and all the rabbits survived, with no respiratory distress. The newly formed cartilage offered sufficient support to the reconstructed larynx. The lining formed from the mucosa of the retention cyst consisted of undiffered stratified squamous cells. This lining membrane was sufficient to control the fibrous tissue response and maintain patency of the restored lumen.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.