Gastric Secretion in Hyperparathyroid Subjects before and after Parathyroid Surgery

Henry Johansson Departments of Surgery, Clinical Research II, Clinical Physiology, and Clinical Chemistry, University Hospital, Uppsala, Sweden

Bengt Furberg Departments of Surgery, Clinical Research II, Clinical Physiology, and Clinical Chemistry, University Hospital, Uppsala, Sweden

Urban Krause Departments of Surgery, Clinical Research II, Clinical Physiology, and Clinical Chemistry, University Hospital, Uppsala, Sweden

Gudmar Lundqvist Departments of Surgery, Clinical Research II, Clinical Physiology, and Clinical Chemistry, University Hospital, Uppsala, Sweden

Åke Rimsten Departments of Surgery, Clinical Research II, Clinical Physiology, and Clinical Chemistry, University Hospital, Uppsala, Sweden

Abstract

In 61 patients with verified hyperparathyreoidism (HPT) the influence of parathyroidectomy on gastric acid and mucus secretion (sialic acid) as well as on serum gastrin concentration was studied. Patients with both normocalcemic (N-HPT) and hypercakemic HPT (H-HPT) have been investigated. The pre-operative serum gastrin level was essentially similar in patients with N-HPT and H-HPT. The serum gastrin level was not influenced by the parathyroidectomy. The gastric acid secretion and the content of sialic acid in the gastric juice were unaffected by parathyroidectomy. Achylia or hypochylia after two different doses of submaximal histamine stimulation were found in 13 patients.

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Gastric Secretion in Hyperparathyroid Subjects before and after Parathyroid Surgery

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Gastric Secretion in Hyperparathyroid Subjects before and after Parathyroid Surgery

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