Serum Beta-2-Microglobulin In Sjogren's Syndrome

Abstract

The serum concentration of beta-2-micro-globulin was determined with a radioimmunoassay in 52 patients with keratoconjunctivitis sicca, 29 of whom had Sjogren's syndrome. Eleven (38%) of the patients with Sjogren's syndrome had high serum values. These cases had a higher mean age and a higher frequency of the complete triad of Sjogren's and of antinuclear antibodies than had the lower value cases. The sicca components per se did not seem to influence the serum concentration of beta-2-microglobulin. Most of the few complications occurred in patients with high values.