Absolute protein quantification, P50
Absorption, P15, P470
Acute lung injury, VEGF, aspirin, P214
Alpha1-acid glycoprotein, P103, P107
Alternative skin model, P447
Aluminum, Acute toxicity, AchE, Rat, P161
Aminoguanidine, apoptosis, doxorubicine, P375
Analytical, P3, P4, P7, P9, P10, P12, P13, P14, P21, P23, P24, P68, P96, P105, P113, P119, P126, P134, P137, P138, P158, P236, P257, P270, P273, P306, P320, P321, P322, P323, P327, P329, P332, P351, P357, P364, P408, P423, P426, P434, P436, P439, P450
Antioxidant Effect, P376
Apoptosis, P245
Apoptosis, Cisplatin, P295
Apoptosis, Vinorelbine, P294
Asbestos, P385
Atypical antipsychotic, P228
Benzodiazepine, P299
Bile acid, A9
Bile Salts, P303
Bioactivation, P354
Bioactivation; Rabbit Liver CYP2B4; Idarubicin; Mitomycin C, P63
Bioavailability, P8, P13, P15, P17, P19, P28, P111, P130, P137, P138, P209, P218, P426, P427, P428, P432, P438, P469, P497
Bioinformatics, P54, P274, P283, P318
Biomarkers, P21, P22, P23, P24, P68, P231, P232, P301, P307, P310, P314, P315, P366, P387, P389, P398, P399, P403, P409, P447, P451
Biotechnology/Nanotechnology, P26, P43, P46, P94, P122, P176, P268, P426, P449
Biotransformation, P332, P353, P356
Blood Brain Barrier, P28, P104, P481
Breast Cancer, P133
Breast Cancer Resistance Protein, A7
Bufadienolides, P459
Carbon nanotubes, P449
Carboxylesterase, P345
Carcinogenesis/Mutagenesis, P29, P30, P31, P32, P33, P34, P35, P36, P91, P188, P261, P281, P294, P295, P373, P399, P410
Cholesterol, P445
Chromium, pulmonary tumors, atomic absorption spectroscopy, P365
Chronic renal failure, P495
Clearance prediction, P37, P38, P39, P42, P73, P77, P97, P136, P143, P146, P154, P236, P273, P342, P426, P435, P482, P487, P507, P510, P520
Conjugation reactions and enzymes, A10, A12, P44, P45, P46, P47, P48, P49, P50, P51, P52, P54, P55, P101, P110, P112, P185, P188, P196, P197, P201, P319, P333, P348, P352, P353, P356, P362, P415, P459
Continuous spectrophotometric assay, P92
Control Sample contamination, P450
Cryopreservation, P247
Cryopreserved Human Hepatocytes (CryoHeps), P73
CYP2A6, P404
CYP2E1, P207
CYPs Endogenous Functions, P60, P83, P93, P219
Cytochrome P450, A3, P19, P30, P42, P57, P61, P62, P65, P67, P68, P69, P72, P75, P78, P79, P80, P86, P87, P88, P89, P90, P91, P92, P93, P94, P95, P97, P98, P99, P143, P145, P146, P147, P151, P156, P160, P173, P176, P177, P178, P179, P180, P181, P184, P186, P193, P195, P197, P198, P199, P200, P203, P205, P206, P208, P212, P213, P219, P220, P226, P227, P240, P243, P244, P247, P249, P262, P268, P278, P279, P280, P282, P283, P284, P286, P289, P296, P314, P322, P331, P342, P351, P352, P353, P354, P356, P359, P364, P366, P373, P397, P404, P406, P411, P414, P417, P419, P432, P433, P438, P444, P449, P455, P457, P458, P485, P492
Cytochrome P450 2C8, P276
Cytochrome P450 BM3, P457
Differences in metabolism (species, gender, age, diseases), A10, P81, P90, P97, P98, P100, P111, P122, P209, P240, P275, P324, P332, P337, P342, P344, P361, P404, P405, P431
Disposition, A5, P17, P23, P37, P40, P103, P104, P105, P106, P107, P108, P109, P110, P112, P122, P130, P134, P150, P293, P330, P349, P350, P360, P370, P427, P428, P432, P437, P438, P439, P461, P462, P463, P466, P468, P472, P479, P497, P498, P501, P502, P503, P516, P517, P518, P519
Distribution, P111
DNA Damage and Repair, P29, P35, P115, P116, P117, P221, P375, P395, P403, P418, P456
DNA methylation, P399
Drosophila melanogaster, survival rate of larva, insecticide, mortality, P174
Drug delivery, P26, P28
Drug discovery and development, A8, P3, P10, A10, P17, P18, P28, P38, P40, P42, P66, P88, P91, P94, P113, P119, P123, P124, P127, P130, P132, P133, P135, P136, P137, P138, P139, P141, P173, P191, P195, P198, P202, P215, P224, P232, P236, P238, P244, P254, P255, P263, P267, P268, P271, P273, P274, P278, P279, P281, P292, P293, P300, P306, P310, P326, P329, P330, P331, P334, P335, P338, P345, P349, P350, P351, P357, P364, P421, P424, P425, P427, P429, P431, P433, P436, P448, P450, P453, P460, P462, P466, P481, P493, P496, P500, P505, P512, P513, P514, P515, P516, P517
Drug Dissolution, P8
Drug induced liver injury, P222
Drug interaction, A8, P25, P44, P47, P48, P55, P66, P67, P70, P75, P91, P121, P144, P148, P149, P150, P151, P152, P154, P155, P179, P190, P192, P197, P198, P200, P201, P206, P207, P208, P222, P240, P255, P283, P433, P435, P460, P463, P464, P467, P469, P473, P477, P478, P486, P488, P490, P492, P494, P500, P509, P510, P514, P515, P516, P517, P519, P520
Efavirenz, P179
Embryotoxicity, P318
Environmental Toxicology, P24, P29, P31, P33, P36, P49, P114, P157, P158, P160, P161, P162, P165, P166, P167, P170, P171, P172, P173, P174, P212, P254, P263, P281, P298, P301, P308, P312, P313, P314, P344, P374, P385, P387, P395, P399, P451
Enzyme Bio-engineering, P82, P88, P94, P175, P176
Enzyme induction, P44, P47, P64, P67, P70, P73, P81, P87, P89, P143, P146, P147, P177, P178, P180, P183, P184, P185, P186, P187, P226, P239, P240, P242, P246, P369, P370, P377, P433, P455
Enzyme inhibition/inactivation, P45, P48, P51, P66, P69, P73, P75, P81, P84, P91, P121, P145, P146, P147, P151, P154, P156, P162, P188, P190, P192, P194, P196, P198, P199, P200, P201, P202, P205, P206, P207, P208, P246, P248, P262, P264, P276, P283, P287, P373, P383, P435, P444, P495
Erythrocyte, P471
Esculetin, P327
Ethanol, P246
Extracellular signal-regulated kinase (ERK), P227
Extrahepatic metabolism, P19, P53, P56, P59, P64, P72, P154, P209, P210, P211, P212, P215, P216, P217, P345, P419
Flavin-containing monooxygenase, P372
Flavonoids, P373
Forced Degradation, P127
Gene expression and regulation, P29, P32, P44, P64, P70, P86, P87, P179, P184, P185, P186, P191, P219, P220, P224, P225, P226, P227, P242, P245, P261, P291, P294, P295, P296, P317, P318, P366, P370, P390, P413, P444, P445, P446, P449, P454, P455, P495, P497, P498, P499, P501, P502, P503, P508, P511
Gene polymorphism, P400
Genetic Polymorphism, P418
Genomics/Metabonomics/Proteomics, P35, P62, P116, P180, P224, P231, P232, P234, P235, P296, P405, P406, P413
Genotoxicity, P165
Genotype, Phenotype, Polymorphism, CYP2D6 null alleles, Iran, Mazandaran, P411
Glutathione S-transferases, P57
Glutathione Transferase, P388
Hepatocytes, A2, A5, A9, A12, P38, P39, P47, P87, P98, P99, P103, P107, P136, P143, P150, P177, P178, P181, P198, P208, P224, P225, P227, P231, P237, P239, P240, P245, P246, P275, P288, P303, P304, P310, P347, P363, P367, P397, P414, P435, P444, P445, P448, P456, P464, P466, P467, P484, P487, P492, P498, P510, P514
Hepatotoxicity, P229
Herb-Drug Interactions, P69, P81, P145, P193, P199, P200, P249, P254, P259, P260, P261, P262, P263, P264, P265, P298
Herbal Medicine-Active Compounds, P184, P193, P248, P252, P253, P254, P256, P257, P262, P263, P264, P298, P311, P314, P339, P376, P390, P415, P430, P442
High throughput techniques, P12, P25, P87, P116, P121, P177, P178, P267, P268, P269, P270, P272, P276, P292, P328, P338, P512, P513, P515
Human ADME, P349
Human liver slices, P507
Humanized animal, P231
Hypercholesterolemia, P383
In Silico, A10, P34, P42, P66, P124, P141, P274, P275, P276, P277, P279, P280, P281, P282, P283, P284, P306, P322, P326, P446, P504, P505
In situ rat intestine-liver preparation, P216
In vitro / in vivo extrapolation, P342, P520
In vitro techniques, A2, A4, P8, A11, P17, P19, P25, P34, P37, P39, P45, P48, P49, P51, P74, P77, P79, P80, P84, P86, P99, P104, P106, P114, P121, P124, P129, P156, P177, P181, P197, P199, P201, P203, P206, P208, P209, P210, P211, P212, P213, P216, P217, P221, P224, P236, P237, P239, P241, P244, P255, P258, P267, P268, P270, P273, P285, P288, P289, P290, P292, P293, P300, P304, P307, P315, P328, P333, P337, P344, P348, P352, P358, P359, P363, P364, P398, P414, P434, P447, P453, P456, P460, P462, P463, P464, P473, P475, P476, P477, P480, P484, P486, P487, P492, P493, P495, P505, P507, P510, P512, P513, P514, P515, P516, P517, P519, P520
Intestinal Absorption, P493
Intestinal motility, prokinetic, P442
Intravenous Admistration, P151
Irreversible Binding, P125
Isothiocyanates, P256
Kidney, A11
Lung, P141
Malignant Mesothelioma, P403
Mass spectrometry, P65
Mechanisms of xenobiotic toxicities, A12, P26, P29, P35, P79, P80, P114, P140, P159, P162, P172, P193, P222, P232, P245, P259, P296, P298, P300, P301, P302, P303, P305, P306, P307, P309, P310, P311, P312, P313, P314, P316, P317, P319, P352, P371, P374, P389, P393, P405, P408, P447, P448
Metabolic profiling, P10, P96, P105, P110, P112, P126, P134, P160, P209, P213, P229, P271, P278, P300, P311, P319, P320, P321, P323, P324, P326, P327, P328, P329, P330, P331, P332, P334, P335, P337, P338, P341, P343, P344, P349, P350, P351, P357, P360, P361, P415, P423, P432, P457
Metabolism, P10, A12, P19, P45, P48, P49, P50, P51, P57, P64, P67, P68, P74, P77, P78, P79, P80, P84, P86, P88, P90, P95, P96, P97, P98, P99, P100, P101, P105, P109, P110, P111, P112, P119, P125, P145, P146, P148, P151, P166, P178, P188, P190, P193, P195, P205, P210, P211, P213, P215, P217, P218, P225, P229, P239, P241, P243, P244, P254, P263, P265, P267, P271, P273, P275, P277, P278, P279, P280, P282, P285, P287, P288, P289, P290, P293, P300, P302, P304, P306, P308, P311, P319, P320, P321, P322, P324, P325, P326, P327, P328, P329, P330, P331, P333, P334, P335, P338, P339, P341, P342, P343, P345, P348, P349, P350, P351, P353, P354, P356, P357, P358, P359, P360, P361, P363, P367, P372, P397, P406, P415, P417, P419, P426, P428, P430, P437, P438, P439, P444, P445, P448, P449, P459, P463, P492, P507, P518
Metabolism-dependent CYP inhibition, P203
Metabolite synthesis, P43
Metal Toxicity, P84, P147, P166, P188, P196, P365, P366, P367, P369, P408
Methotrexate Hepatotoxicity Omega3 Selenium, P394
MIST, Microdosing, P126
Mitragyna speciosa, P199
Mixture effect, P258
MRP2, P473
NAT2, P223
Nephrotoxicity, A4, P317
Nitric oxide, P202
Non-P450 phase I enzymes, P49, P110, P180, P201, P215, P218, P247, P333, P334, P335, P345, P355, P361, P370, P372
Nuclear receptor, P226
Nutrition, P489
Nutrition and Cancer Prevention, P249
Nutrition and Chemoprevention, P258
O-glycosylation, prediction, P20
OATPs in liver cancer, P483
Occupational, P387
Ochratoxin A, Foods, P452
On-Line Radiochromatography, P423
Oral contraceptives, P230
Oxidative Stress, P21, P47, P72, P114, P117, P120, P140, P166, P167, P185, P189, P222, P242, P245, P246, P256, P258, P259, P262, P298, P304, P312, P313, P318, P374, P375, P376, P378, P379, P380, P383, P385, P386, P388, P389, P391, P392, P393, P395, P396, P405, P408, P443, P501, P508
Paraoxonase 1, P416
Parkinson’s Disease, P191
PBPK Modeling, P40
Peroxidase, P369
Pharmaceutics, P272
Pharmacogenetics/Pharmacoepigenetics, P68, P75, P81, P99, P101, P176, P287, P308, P355, P398, P399, P400, P401, P402, P404, P405, P407, P409, P410, P411, P414, P415, P416, P419, P420, P458, P511
Pharmacokinetics, P129
Pharmacokinetics and Pharmacodynamics, A5, A7, A8, P8, P11, P14, P17, P23, P28, P39, P42, P45, P96, P104, P105, P106, P113, P119, P121, P122, P134, P136, P143, P145, P148, P255, P270, P271, P275, P285, P291, P308, P330, P339, P343, P350, P406, P413, P421, P422, P424, P425, P430, P431, P432, P433, P437, P438, P439, P441, P446, P468, P478, P479, P480, P481, P482, P491, P493, P500, P504, P506, P510
Pharmcokinetics, P494
Phenotyping; Deoxyschizandrin; Approximate maximal initial metabolite formation rate, P78
Phthalate, P386
Physiologically based Pharmacokinetics, P154
Placenta, P220
Plasma protein binding, P106
Plated culture, P243
Polyphenol, P391
Polyphenol oxidase, P175
Positron Emission Tomography, P500
Prodrug, P119
Prodrugs, P120
progesterone, castration,antioxidant enzymes, P316
Protein interaction, P362
Psilocin, P51
Quercetin, P69
Radio-labeling, P434
Radiotoxicity, P366
Reactive Metabolite, P448
Reactive metabolites, P358, P453
Receptors/nuclear receptors, P44, P124, P147, P185, P186, P219, P220, P225, P227, P232, P242, P255, P400, P442, P443, P445, P446, P454
Recombinant UGT, P267
Refinement and replacement animals, P436
Regioselectivity, P282
Risk Assessment, P21, P24, P31, P33, P34, P57, P111, P125, P158, P160, P197, P281, P301, P324, P352, P361, P385, P389, P410, P413, P418, P419, P435, P450, P451, P452, P453
Schisandrins, P265
Serotonin, Alcohol dependence, P402
SiRNA/microRNA, A2, A4, P116, P126, P222, P225, P454
Spinal cord injury, P392
Stem Cell Research, P35, P115, P116, P296, P397, P456
Stereoselective metabolism, P52, P353, P458, P459
Structural elucidation, P326, P343
Structure and metabolism relationship, A10
Targeting, A8
Therapy, P21, P234
Thiopurine, P420
Tiapride, P439
Transporters, A7, A9, A12, P15, P37, P41, P73, P98, P104, P130, P144, P149, P150, P155, P156, P179, P190, P236, P237, P239, P253, P285, P303, P397, P402, P409, P429, P455, P460, P462, P463, P464, P465, P466, P467, P471, P472, P475, P476, P477, P478, P480, P481, P484, P485, P486, P487, P489, P491, P493, P495, P497, P498, P499, P500, P501, P502, P504, P505, P507, P509, P511, P513, P514, P515, P516, P517, P518
Triple Quadrupole vs. Orbitrap, P338
Troxerutin; High-fat diet; Oxidative stress, P251
UGT enzymes, P59
UPLC/MS/MS, P14
Uremic toxin, P396
Valproic Acid, P304
Warfarin, P407
Whole-Cell biotransformation with P450s, P176
X-ray Crystallography, P139
Xenobiotic Metabolizing Enzymes, P412
Zebrafish liver microsomes, P286