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Hemoglobin
international journal for hemoglobin research
Volume 10, 1986 - Issue 2
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Original Article

Hemoglobin san diego/β→ thalassemia in a greek adult

D. Loukopoulos Department of Medicine, University of Athens Laikon General Hospital, Athens, 11527, Greece
,
C. Poyart Unite INSERM U.27, Hopital Foch, 92150, Suresnes, France
,
J. Delanoe-Garin Unite INSERM U.91, Hopital Henri Mondor, 94010, Creteil, France
,
C. Matsis Department of Medicine, University of Athens Laikon General Hospital, Athens, 11527, Greece
,
N. Arous Unite INSERM U.91, Hopital Henri Mondor, 94010, Creteil, France
,
J. Kister Unite INSERM U.27, Hopital Foch, 92150, Suresnes, France
,
A. Loutradi-Anagnostou Department of Medicine, University of Athens Laikon General Hospital, Athens, 11527, Greece
,
Y. Blouquit Unite INSERM U.91, Hopital Henri Mondor, 94010, Creteil, France
,
Ph. Fessas Department of Medicine, University of Athens Laikon General Hospital, Athens, 11527, Greece
,
J. Thillet Unite INSERM U.91, Hopital Henri Mondor, 94010, Creteil, France
,
J. Rosa Unite INSERM U.91, Hopital Henri Mondor, 94010, Creteil, France
&
F. Galacteros Unite INSERM U.91, Hopital Henri Mondor, 94010, Creteil, France
 show all
Pages 143-159 | Received 08 May 1985, Accepted 10 Oct 1985, Published online: 07 Jul 2009
 
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Abstract

Interaction of β→ thalassemia with Hb San Diego [a high affinity hemoglobin variant, α2β2109(G11)Val→Met] in a 29-year-old Greek male is described. A marked polycythemia with low MCH and MCV, but minor clinical problems were observed. Functional properties of the isolated variant are described.

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