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Drug Development and Industrial Pharmacy Volume 12, 1986 - Issue 6
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Research Article

DSC Screening for Drug-Drug and Drug-Excipient Interactions in Polypharmaceuticals Intended for the Alleviation of the Symptoms of Colds and Flu. I

S. A. Botha Departments of Pharmaceutics and Pharmaceutical Chemistry, Potchefstroom University for C.H.E., Potchefstroom, 2520, South Africa; Research Institute for Industrial Pharmacy, Potchefstroom University for C.H.E., Potchefstroom, 2520, South Africa
,
J. L. Du Preez Departments of Pharmaceutics and Pharmaceutical Chemistry, Potchefstroom University for C.H.E., Potchefstroom, 2520, South Africa; Research Institute for Industrial Pharmacy, Potchefstroom University for C.H.E., Potchefstroom, 2520, South Africa
&
A. P. Lötter Departments of Pharmaceutics and Pharmaceutical Chemistry, Potchefstroom University for C.H.E., Potchefstroom, 2520, South Africa
Pages 811-827 | Published online: 20 Oct 2008
 
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Abstract

DSC screening for drug-drug and drug-excipient interactions of a polypharmaceutical capsule dosage form containing acetaminophen, diphenhydramine hydro= chloride, phenylephrine hydrochloride, ascorbic acid and magnesium stearate was performed. The results show the following:

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