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Research Article

Relationship of dissolution rate in anionic polymeric solutions to viscosity

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Pages 201-213 | Published online: 20 Oct 2008
 

Abstract

The influence of viscosity on the dissolution rate of m-acetotoluidide in aqueous solutions of acacia, gelatin type B, sodium carboxymethylcellulose, sodium alginate and xanthan gum was investigated. The viscosity was measured by a rotational viscometer. The dissolution rates decreased as the viscosities of solutions of anionic polymers increased. The curves representing the relationship of dissolution rate and viscosity varied for each polymeric solution depending on the structural characteristics of the polymer.

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