Abstract
The microindentation technique provides a means of evaluating a number of parameters that characterize the mechanical behavior of single crystals, including plasticity, elasticity, fracture toughness, and the activation volume and activation energy of the associated deformation kinetics. These values have been incorporated into models which predict the pseudostatic compaction and tablet stress relaxation of a number of pharmaceutical materials. Ultimately, the goal is to produce a model to predict dynamic compaction and the strength of the resultant tablet.