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Original Article

Tomographic evaluation of size and X-ray density of normal and denervated human muscles

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Pages 193-200 | Accepted 01 Jul 1981, Published online: 28 Jul 2009
 

Abstract

Summary

Neuromuscular disease will lead to size changes, degeneration or destruction of muscle fibres. However, fat or connective tissue infiltration occurs and this prevents the use of simple measures to assess wasting. Computerized tomography will allow accurate assessment of this wasting. Five normal subjects and five patients with total traumatic denervation of radial or peroneal origin were examined. Denervated muscle was shown to have lower than normal cross-section and X-ray density. These reductions were not paralleled in circumference or limb volume. Recovery could be followed by tomography.

Résumé

Les maladies neuromusculaires entraiˇnent le changement de taille, la dégénérescence ou la destruction des fibres musculaires. Toutefois, l'infiltration de graisse ou de tissu connectif a lieu et rend impossible l'utilisation de mesures simples pour évaluer le degré de dégénérescence. La tomographie informatisée permet l'évaluation exacte de cette dégénérescence. Cinq sujets normaux et cinq patients ayant une dénervation traumatique totale d'origine radiale ou péronéale ont été examinés. Il s'est avéré que le muscle dénervé avait une coupe transversale et une densité aux rayons X inférieures à la normale. Ces réductions n'apparaissaient pas dans la circonférence ou le volume du membre. On a pu suivre la guérison par tomographie.

Zusammenfassung

Ein neuromuskuläres Leiden führt zu Grössenanderung, Degeneration oder Zerstörung von Muskelfasern. Fett oder Bindegewebe dringt durch, und dies hindert die Anwendung von einfachen Massnahmen, um Schwund zu berechnen. Komputerisierte Tomographie gestattet genaue Berechnung von solchem Schwund. Fünf normale Versuchspersonen und fünf Patienten mit totaler traumatischer Denervierung radialen oder peronealen Ursprungs wurden untersucht. Denervierter Muskel zeigte kleinere Dichte im Querschnitt und im Röntgen. Diese Reduktionen hatten keine Parallelen im Umfang oder Volumen der Gliedmassen. Die Genesung konnte durch die Tomographie gefordert werden.

Additional information

Notes on contributors

M. F. Rolfo

It is with great sadness that we have to inform the readership of the Journal that shortly after completing the final editorial work on this Special Issue, Professor Kalman Jacob Mann was seriously injured in a car accident and subsequently died.

Professor Mann was responsible for establishing the two Hadassah Hospitals and Community Health Centres in Jerusalem and for the past 20 years headed the Presidium of Yad Sarah, Israel's largest community based, volunteer operated organization which provides a spectrum of free or nominal cost home care services nation-wide.

We offer our condolences to his family and friends, and trust that this Special Issue stands as a testament to his work in the field.

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