Advanced search
Publication Cover
Cancer Investigation Volume 30, 2012 - Issue 2
Submit an article Journal homepage
118
Views
3
CrossRef citations to date
0
Altmetric
CELLULAR AND MOLECULAR BIOLOGY

Arsenic Trioxide Increases the Sensitivity of 786–0 Renal Carcinoma Cells to Radiotherapy

Yu SuDepartments of Urinary Surgery, Clinical Laboratory, and Radiotherapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China, Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
,
XiaoMin WangDepartments of Urinary Surgery, Clinical Laboratory, and Radiotherapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China, Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, ChinaCorrespondence[email protected] [email protected]
,
WanHai XuDepartments of Urinary Surgery, Clinical Laboratory, and Radiotherapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China, Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
,
Li XueDepartments of Urinary Surgery, Clinical Laboratory, and Radiotherapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China, Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
,
ChunBo HeDepartments of Urinary Surgery, Clinical Laboratory, and Radiotherapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China, Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
,
DeJun YangDepartments of Urinary Surgery, Clinical Laboratory, and Radiotherapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China, Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China
&
RuiHua AnDepartments of Urinary Surgery, Clinical Laboratory, and Radiotherapy, The Fourth Affiliated Hospital of Harbin Medical University, Harbin, China, Department of Urinary Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, ChinaCorrespondence[email protected] [email protected]
 show all
Pages 114-118 | Published online: 02 Feb 2012
 
Sample our Medicine, Dentistry, Nursing & Allied Health journals, sign in here to start your FREE access for 14 days

Abstract

We evaluated the combined effect of As2O3 and ionizing radiation on cultured renal carcinoma cells. The cells receiving both As2O3 and radiotherapy had more DNA damage, more apoptosis, more reactive oxygen species produced, more cells in G2/M phase, and a lower mitochondrial membrane potential than cells treated with As2O3 only or with radiotherapy only (for all comparisons, p < .05). Renal carcinoma cells can be sensitized to ionizing radiation with As2O3, and combining As2O3 and radiation had larger effects than As2O3 only or radiation only.

ACKNOWLEDGMENTS

This work was supported by the Fourth Affiliated Hospital of Harbin Medical University. I would like to thank my advisor for reading and carefully reviewing this manuscript.

Log in via your institution

Access through your institution

Log in to Taylor & Francis Online

Restore content access

Restore content access for purchases made as guest
Purchase options * Save for later

PDF download + Online access

  • 48 hours access to article PDF & online version
  • Article PDF can be downloaded
  • Article PDF can be printed
USD 65.00 Add to cart

Issue Purchase

  • 30 days online access to complete issue
  • Article PDFs can be downloaded
  • Article PDFs can be printed
USD 1,193.00 Add to cart

* Local tax will be added as applicable

Related Research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.