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Research Article

Deprivation Amblyopia and Congenital Hereditary Cataract

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Pages 321-326 | Received 02 May 2013, Accepted 11 Jul 2013, Published online: 18 Oct 2013
 

Abstract

Amblyopia is a neurodevelopmental disorder of vision associated with decreased visual acuity, poor or absent stereopsis, and suppression of information from one eye.CitationCitation Amblyopia may be caused by strabismus (strabismic amblyopia), refractive error (anisometropic amblyopia), or deprivation from obstructed vision (deprivation amblyopia).Citation In the developed world, amblyopia is the most common cause of childhood visual impairment,Citation which reduces quality of lifeCitation and also almost doubles the lifetime risk of legal blindness.CitationCitation Successful treatment of amblyopia greatly depends on early detection and treatment of predisposing disorders such as congenital cataract, which is the most common cause of deprivational amblyopia. Understanding the genetic causes of congenital cataract leads to more effective screening tests, early detection and treatment of infants and children who are at high risk for hereditary congenital cataract.

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