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International Reviews of Immunology Volume 30, 2011 - Issue 2-3
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Research Article

Immune Therapy for Ovarian Cancer: Promise and Pitfalls

Suzanne R. ThibodeauxDepartment of Medicine, School of Medicine and Department of Cellular and Structural Biology, Graduate School in Biomedical Sciences, and the Cancer Therapy and Research Center, University of Texas Health Science Center, San Antonio, Texas, USA
&
Tyler J. CurielDepartment of Medicine, School of Medicine and Department of Cellular and Structural Biology, Graduate School in Biomedical Sciences, and the Cancer Therapy and Research Center, University of Texas Health Science Center, San Antonio, Texas, USACorrespondence[email protected]
Pages 102-119 | Published online: 10 May 2011
 
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Abstract

This review covers immune and anatomic considerations specific for ovarian cancer immune therapy. Prior approaches and potential reasons for lack of better efficacy are discussed, along with newer approaches in pre-clinical and early clinical development. Potential means for future investigations and means to integrate immune with other approaches are discussed.

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