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Research Article

Perspective for Prophylaxis and Treatment of Cervical Cancer: An Immunological Approach

, , , , , , , , , , & show all
Pages 3-21 | Accepted 30 Oct 2011, Published online: 17 Jan 2012
 

Abstract

As the second most common cause of cancer-related death in women, human papilloma virus (HPV) vaccines have been a major step in decreasing the morbidity and mortality associated with cervical cancer. An estimated 490,000 women are diagnosed with cervical cancer each year. Increasing knowledge of the HPV role in the etiology of cervical cancer has led to the development and introduction of HPV-based vaccines for active immunotherapy of cervical cancer. Immunotherapies directed at preventing HPV-persistent infections. These vaccines are already accessible for prophylaxis and in the near future, they will be available for the treatment of preexisting HPV-related neoplastic lesions.

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