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Immunopharmacology and Immunotoxicology Volume 34, 2012 - Issue 1
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Research Article

Anticomplement activity of isolated compounds from Artemisia montana

Hyung-In MoonDepartment of Medicinal Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan, South KoreaCorrespondence[email protected]
,
Seil Jung
,
Young-Choon LeeDepartment of Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan, South Korea
&
Jai-Heon LeeDepartment of Medicinal Biotechnology, College of Natural Resources and Life Science, Dong-A University, Busan, South Korea
Pages 113-115 | Received 20 Apr 2011, Accepted 21 Apr 2011, Published online: 31 May 2011
 
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Abstract

The study evaluated the anticomplement activity from isolated compounds from Artemisia montana (Nakai) Pamp. from South Korea on the classical pathway. In a previous work, A. montana (Nakai) Pamp. chloroform extracts showed inhibitory activity against complement system. The chromatographic separation of a chloroform chloride extract of A. montana (Nakai) Pamp. led to the isolation of four compounds. Their structures were characterized to be ezoartemin (1), yamayomoginin (2), ezomontanin (3) and 11,13-dihydroezomontanin (4) by spectroscopic data. This is the first report of anticomplement activity of isolated compounds from A. montana (Nakai) Pamp.

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