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Abstract
Purpose: Comparison between the risk of recurrence during pregnancy with nonpregnant periods in patients with ocular toxoplasmosis (OT).
Methods: Records of 40 women were retrospectively reviewed. The women were subdivided into either a pregnant group or a control group formed by nonpregnant women during follow-up. Comparable cases from the literature were added. Mean number of recurrences per year was compared.
Results: Eleven women with pregnancies could be included. Six cases from the literature were added (total n = 17). Mean number of recurrences per year during versus not during pregnancy was 0.16 (SD 0.39) versus 0.32 (SD 0.30; p = 0.088), respectively. In the control group (n = 29) the mean number of recurrences per year (0.31; SD 0.27) was significantly higher when compared to cases during pregnant periods (p = 0.002).
Conclusion: Adding to published series, the presented data do not provide evidence for a relevant impact of pregnancy on recurrence behavior in OT.
Declaration of interest
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.
FM has been primary investigator in several industry-sponsored trials in the last 2 years (Abbott, Allergan, Esbatech, Novatis), has served on an advisory board for Allergan, and received lecture honoraria by Heidelberg Engineering. These organizations had no role in the design or conduct of the research.
Funding was provided through an MRe Scholarship from the Studienstiftung des deutschen Volkes. The funding organization had no role in the design or conduct of the research.
Notes
* We presented the results of this study at the AUS meeting, May 2013 in Seattle, Washington.