Statistical analyses of Endogenous Uveitis Patients (2007–2009) in central Tokyo area and Comparison with Previous Studies (1963–2006)

Abstract

Purpose: To investigate the frequencies of the diseases in the new patients with uveitis during 2007–2009 and compare them with previously-reported data from the University of Tokyo Hospital.

Methods: We retrospectively analyzed the clinical records of patients who visited the outpatient clinic from January 2007 to December 2009, and compared them with those of 1963–2006.

Results: During 2007–2009, 468 new patients visited our hospital. Definite diagnoses were made in 63.0%. Frequent diagnoses include sarcoidosis (9.4%), Vogt-Koyanagi-Harada (VKH) disease (7.9%), herpetic iritis (6.0%), Behçet’s disease (5.6%), Posner-Schlossman syndrome (4.3%), HLA-B27-associated uveitis (3.0%), and intraocular malignant lymphoma (2.8%). Compared with our former findings, the ratios of sarcoidosis, herpetic iritis, CMV retinitis, Fuch’s heterochromic iridocyclitis, acute retinal necrosis and intraocular lymphoma increased, while that of Behçet’s disease decreased.

Conclusions: Top three uveitis during 2007–2009 were sarcoidosis, VKH disease, herpetic iritis. Reduced frequency of Behçet’s disease was one of the most prominent characteristics.

• Behçet’s disease
• endogenous uveitis
• sarcoidosis
• statistical analysis
• Vogt-Koyanagi-Harada disease

Acknowledgement

This study was supported in part by a Grant-in-Aid for Science Research for Behçet’s disease from the Ministry of Health, Labour and Welfare of Japan (No. 50056096).

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.