Comparison of Enhanced Depth Imaging and Swept Source Optical Coherence Tomography in Assessment of Choroidal Thickness in Vogt–Koyanagi–Harada Disease

ABSTRACT

Purpose: To compare enhanced depth imaging (EDI-OCT) and swept source optical coherence tomography (SS-OCT) in assessment of Vogt–Koyanagi–Harada (VKH) disease.

Methods: All consecutive VKH patients seen at Singapore National Eye Centre during 2012–2013 were imaged using both modalities. Subfoveal choroidal thickness (SFCT) was measured by one masked trained observer.

Results: A total of 137 pairs of scans were obtained from 48 patients. SFCT was more likely to be measurable on SS-OCT than EDI-OCT (112, 81.8%; 84, 61.3%; p<0.001 Fisher’s Exact test). There was good inter-OCT correlation of SFCT when both scans were measureable (mean of the difference in SFCT ± 2 standard deviations (SD) of –14.5 ± 21.0 μm).

Conclusions: SS-OCT images are superior to EDI-OCT but the SFCT measurements are comparable when both are readable.

Keywords:

• Assessment
• enhanced depth imaging
• optical coherence tomography
• swept source
• Vogt–Koyanagi–Harada

DECLARATION OF INTEREST

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.