Cancer and fertility preservation: Barcelona consensus meeting

Abstract

Improvements in early diagnosis and treatment strategies in cancer patients have enabled younger women with cancer to survive. In addition to the stressful event of the diagnosis, patients with malignant diseases face the potential loss of the opportunity to have children. Preservation of fertility has become a challenging issue and it is still surrounded by controversies. On the basis of available evidence, a group of experts reached a consensus regarding the options for trying to preserve fertility in women with cancer: among established methods, in postpubertal women, oocyte cryopreservation is the preferred option, whereas ovarian tissue cryopreservation is the only possibility for prepubertal girls. Combining several strategies on an individual basis may improve the chances of success. Realistic information should be provided before any intervention is initiated. Counseling should offer support for patients and provide better care by understanding emotional needs, psychological predictors of distress and methods of coping. Early referral to the fertility specialist is essential as fertility preservation (FP) may improve quality of life in these patients. The information summarized here is intended to help specialists involved in the treatment of cancer and reproductive medicine to improve their understanding of procedures available for FP in young cancer patients.

• Cancer
• consensus
• fertility preservation
• oocyte vitrification
• ovarian tissue cryopreservation

Acknowledgements

This study was performed under the auspices of Cátedra d’Investigació en Obstetricia i Ginecología of the Department of Obstetrics and Gynecology, Institut Universitari Dexeus, Universitat Autònoma de Barcelona. The authors are grateful to the assistance provided by Fundación Dexeus Salud de la Mujer and BIOCAT. They also thank Marta Pulido, MD, for editing the manuscript.