A case of postmenopausal androgen excess

Abstract

Ovarian steroid cell tumors are very rare but potentially life-threatening neoplasms. They represent less than 0.1% of all ovarian tumors, typically present in premenopausal women and frequently manifest with virilization. Signs of hyperandrogenism may appear in postmenopausal women due to tumorοus and non-tumorοus adrenal and ovarian causes as well due to the normal aging process. In any case, steroid cell tumor should be suspected in postmenopausal women who present with rapid progressive androgen excess symptoms. This report describes a case of a 67-year-old postmenopausal woman with signs of hyperandrogenism, where an ovarian steroid cell tumor was diagnosed and treated by laparoscopic bilateral salpingo-oophorectomy and synchronous hysterectomy.

Chinese abstract

卵巢类固醇细胞肿瘤是一种非常罕见但是可以威胁生命的肿瘤。在卵巢所有类型肿瘤中所占比例不到0.1%，经常发生于绝经前女性，最显著的表现是出现男性化。由于绝经后女性肿瘤和非肿瘤性肾上腺和卵巢的原因，以及正常老化过程，高雄激素血症的症状可能会出现于绝经后女性。在任何情况下，当绝经后女性出现快速发展的雄激素过多的症状时，都应该考虑是否患有卵巢类固醇细胞肿瘤。这篇文章报道了一个出现高雄激素血症的67岁绝经后女性，诊断为卵巢类固醇细胞肿瘤，进行了腹腔镜下双附件及全子宫切除术。

• Androgen excess
• ovarian tumor
• postmenopause
• salpingo-oophorectomy
• virilization

Declaration of interest

The authors report that they have no conflicts of interest.