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Abstract
The objective of this study was to assess the iodine status of pregnant women in a metropolitan city which was stated as iodine sufficient area after salt iodination program. This multicenter, cross-sectional study was carried out on 3543 pregnant women. Age, gestational weeks, smoking, consumption of iodized salt, dietary salt restriction, history of stillbirth, abortus and congenital malformations were questioned. Spot urine samples were analyzed for urine iodine concentration (UIC). The outcomes were: (a) median UIC in three trimesters of pregnancy and (b) frequency of ID among pregnant women. The median UIC was 73 µg/L. The median UIC was 77 µg/L (1–324), 73 µg/L (1–600) and 70 µg/L (1–1650) in three trimesters of pregnancy, respectively (p: 0.14). UIC <50 µg/L was observed in 36.6% (n: 1295) and UIC<150 µg/L was observed in 90.7% (n: 3214) of pregnant women. Only 1% (n: 34) of the pregnant women had UIC levels higher than 500 µg/L. This study showed that more than 90% of the pregnant women in this iodine-sufficient city are facing some degree of iodine deficiency during their pregnancy. A salt iodization program might be satisfactory for the non-pregnant population, but it seems to be insufficient for the pregnant population.
Chinese abstract
本项研究的目的是评估生活在碘充足的大城市孕妇施行食盐加碘方案后碘营养状况。本研究采用多中心、横断面研究，包括3543名孕妇。分析孕妇的年龄、孕周、吸烟史、碘盐摄入情况、限盐膳食情况、死胎、流产及胎儿先天畸形情况。随机尿样本分析尿碘浓度（UIC）。结果：(a)：孕妇孕早、中、晚期UIC中位数及(b)：碘缺乏（ID）发生率。UIC中位数为73 mg/L。孕三期孕妇UIC中位数分别为77 mg/L (1-324), 73 mg/L (1-600) 和70 mg/L (1-1650) (p: 0.14)。UIC < 50 mg/L占36.6%(n: 1295)，UIC < 150 mg/L 占90.7%(n: 3214)，只有1%的孕妇UIC水平高于500mg/L(n: 34)。本研究显示生活在碘充足的大城市，超过90%的孕妇孕期存在一定程度的碘缺乏。食盐加碘计划可能满足于非妊娠人群，但对于孕妇而言似乎并不充足。
Declaration of interest
There is no conflict of interest and this paper has not been funded by any organization or company.