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Letter to the Editor

Magnitude to thrombocytopenia among the patients with novel Middle East respiratory syndrome

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Page 612 | Received 11 Jun 2014, Accepted 12 Jun 2014, Published online: 01 Jul 2014

To the Editor,

Middle East respiratory syndrome (MERS) is one of the new problematic emerging respiratory viral infection originated from the Middle East [Citation1–3]. This disease becomes a new concern on its possible worldwide pandemic. Generally, the patient has acute febrile illness with respiratory symptoms [Citation1–3]. Pneumonia is common and the fatality is high [Citation1–3]. Apart from respiratory presentation, there are also uncommon presentations. Thrombocytopenia is an interesting hematological manifestation of MERS. However, the exact magnitude of the problem has never been clarified. Here, the authors try to summarize and assess the magnitude of thrombocytopenia among the patients with MERS. Based on available data on 164 published cases with MERS [Citation4–6], 125 cases had thrombocytopenia giving the prevalence rate equal to 76.2%. This rate is considerably high as compared to the newly emerging respiratory viral infections. It might conclude that thrombocytopenia is an important clinical presentation in MERS and can be a useful basic laboratory finding to support diagnosis of MERS. The pathophysiology of thrombocytopenia in MERS is the interesting topic for further study.

Declaration of interest

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.

References

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  • Wiwanitkit V. Novel Middle East respiratory syndrome coronavirus. J Formos Med Assoc. 2014;113(1):65
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  • Omrani AS, Matin MA, Haddad Q, Al-Nakhli D, Memish ZA, Albarrak AM. A family cluster of Middle East Respiratory Syndrome Coronavirus infections related to a likely unrecognized asymptomatic or mild case. Int J Infect Dis 2013;17:e668–e672
  • Assiri A, Al-Tawfiq JA, Al-Rabeeah AA, Al-Rabiah FA, Al-Hajjar S, Al-Barrak A, Flemban H, Al-Nassir WN, Balkhy HH, Al-Hakeem RF, et al. Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: A descriptive study. Lancet Infect Dis 2013;13:752–761

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