A case of subcorneal pustular dermatosis in association with monoclonal IgA gammopathy successfully treated with acitretin

Abstract

Subcorneal pustular dermatosis (SPD), or Sneddon–Wilkinson disease, is a rare, chronic, recurrent, pustular eruption. Association with several diseases is well known, mainly IgA and IgG gammopathies or myelomas. Although dapsone is often considered to be the first-line treatment, some patients fail to respond or cannot tolerate the side effects. For cases that do not respond well to this treatment, acitretin, an excellent second-line treatment, may be used. Herein, a 55-year-old woman with SPD associated with monoclonal IgA gammopathy refractory to dapsone is presented, who was successfully treated with acitretin in a short period.

Keywords::

• acitretin
• pustular dermatosis

Declaration of interest:

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.