Ulcerative cutaneous polyarteritis nodosa treated with mycophenolate mofetil and pentoxifylline

Abstract

Cutaneous polyarteritis nodosa (CPAN) is a self-limited cutaneous vasculitis characterized by painful nodules, affecting mostly the lower limbs, and livedo reticularis. Despite its benign course, CPAN may display a chronic relapsing evolution with repeated exacerbations. Ulcerative CPAN has a more prolonged evolution and is associated with peripheral neuropathy. We report on a patient with a 20-year history of ulcerative and painful CPAN, refractory to multiple immunosuppressive treatments, treated successfully by mycophenolate mofetil and pentoxifylline.

Key words::

• ivedo
• mycophenolate mofetil
• pentoxifylline
• polyarteritis nodosa
• vasculitis

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.