Comparison of the effect of high fruit and soybean products diet and standard diet interventions on serum uric acid in asymptomatic hyperuricemia adults: an open randomized controlled trial

Abstract

The aim of this study was to compare the effect of high fruit and soybean products diet and standard diet interventions on serum uric acid (SUA) in asymptomatic hyperuricemia adults. A total of 187 Chinese adults (20–59 years old) with asymptomatic hyperuricemia participated in this randomized trial and were assigned to receive the standard diet recommended by guideline (group 1) and high fruit and soybean products diet (group 2) for 3 months. The outcome of SUA was assessed before and at the end of the intervention period. After 3 months, the SUA in group 1 and group 2 was significant reduced, whereas the SUA was not significantly changed in-between groups. These data suggest that over a 3-month period, although the high fruit and soybean products diet and standard diet interventions yield no different effects on SUA, the high fruit and soybean products dietary intervention could be an effective alternative to a standard diet for achieving clinically important reductions in SUA for asymptomatic hyperuricemia patients.

Keywords:

• Dietary intervention
• insulin resistance
• metabolic syndrome

Acknowledgements

We express our appreciation to all of the study participants and the staff of the Health Examination Center of Heping District in Tianjin for their assistance.

Disclosure statement

The authors declare that they have no conflicts of interest.

Funding information

This research was supported by the National Science and Technology Support Program (No. 2012BAI02B02), National Natural Science Foundation of China (No. 81502809), National Natural Science Foundation of China (No. 81302422) and the Innovation Funding for graduates of Tianjin Medical University, the third phase of the 211 Project for Higher Education (No. 2009GSI05).