Dietary total antioxidant capacity is associated with plasmatic antioxidant capacity, nutrient intake and lipid and DNA damage in healthy women

Abstract

Dietary total antioxidant capacity (DTAC) seems to be associated with reducing risk of diseases. However, data about the influence of the DTAC on oxidative stress parameters are scarce. The aim of this study was to estimate the DTAC and its influence on plasma total antioxidant capacity (PTAC), and damage to lipids, proteins and DNA in healthy women. It was found a positive correlation between DTAC and PTAC in young and healthy subjects, where presumably the endogenous defenses are fully functional. DTAC and PTAC were positively correlated with the intake of known antioxidants, including vitamin C and polyphenols. The DTAC exhibited a negative correlation with lipid oxidative damage, while PTAC showed a negative correlation with DNA damage. This data contributes to better understanding of the recommended dietary antioxidant intake for promoting health.

Keywords:

• Antioxidants
• diet
• oxidative stress

Acknowledgements

The authors would like to thank all those who volunteered to take part in the study.

Disclosure statement

The authors declare there is no conflict of interest regarding the manuscript submitted.

Funding information

This study was funded by grants from PRONEX/CNPq and the University of Caxias do Sul. Mirian Salvador is the recipient of a CNPq Research Fellowship and Natalia Stedile is the recipient of a CAPES Research Fellowship.