Alternative technique for intrafemoral injection and bone marrow sampling in mouse transplant models

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Acknowledgements

We thank J. Vormoor and Ch. LeViseur for initial help with intrafemoral transplants. G. Cario, M. Stanulla, and M. Schrappe from the ALL-Berlin–Frankfurt–Münster (BFM) study group provided the patient samples. These originated from patients enrolled in the ALL-BFM 2000 study who had given informed consent in accordance with the Declaration of Helsinki. Approval was obtained from the Institutional Review Board (IRB) of the Medical School Hannover and the local IRB for all participating centers in the trial ALL-BFM 2000. This study wassupported by the Swiss National Science foundation (grant no 310030-118392), by the Novartis Foundation for biomedical research, and by the Vontobel-Stiftung.

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