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Leukemia & Lymphoma Volume 53, 2012 - Issue 2
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Research Article

Clinicopathologic features and outcome of acute erythroid leukemia based on 2008 revised World Health Organization classification

Chia-Jen LiuDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, Taiwan
,
Ying-Chung HongDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, TaiwanCorrespondence[email protected]
,
Ching-Fen YangDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taipei, Taiwan
,
Shih-Hao LiuDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;Department of Pathology and Laboratory Medicine, Koo Foundation Sun Yat-Sen Cancer Center, Taipei, Taiwan
,
Jyh-Pyng GauDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, Taiwan
,
Jin-Hwang LiuDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, Taiwan
,
Liang-Tsai HsiaoDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, Taiwan
,
Chun-Yu LiuDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, Taiwan
,
Yuan-Bin YuDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, Taiwan
&
Cheng-Hwai TzengDivision of Hematology and Oncology, Department of Medicine, Taipei, Taiwan;School of Medicine, National Yang-Ming University, Taipei, Taiwan
 show all
Pages 289-294 | Received 06 Feb 2011, Accepted 20 Jul 2011, Published online: 23 Sep 2011
 
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Abstract

We report 67 patients with acute erythroid leukemia (erythroleukemia) based on the World Health Organization (WHO) 2008 classification. Reviewing the clinicopathologic features, cytogenetics and outcomes, the characteristics of erythroleukemia resembled myelodysplastic syndromes (MDS). Patients with poor performance status, advanced anemia and poor-risk cytogenetics had significantly inferior outcomes. The International Prognostic Scoring System (IPSS) for MDS is useful to differentiate the prognosis of erythroleukemia.

Acknowledgements

This work was supported in part by grants from the Taipei Veterans General Hospital (V100A-004) and the Taiwan Clinical Oncology Research Foundation.

Potential conflict of interest:

Disclosure forms provided by the authors are available with the full text of this article at www.informahealthcare.com/lal.

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