Cell Proliferation Markers in Acute Leukemia

Abstract

Cell proliferation of blast cells in acute myeloid leukemia (AML) plays a major role in determining response to therapy. Therefore, studies of leukemic cell growth and related factors have been very numerous involving many techniques. They have used a wide panel of proliferation markers but despite their close correlation, we consider here markers assessing cell cycle parameters and those related to cell proliferation.

Key Words:

• AML
• cell
• growth
• cell cycle