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Review Article

Nanocarrier possibilities for functional targeting of bioactive peptides and proteins: state-of-the-art

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Pages 114-141 | Received 28 Jul 2011, Accepted 27 Sep 2011, Published online: 24 Oct 2011
 

Abstract

This review attempts to provide an updated compilation of studies reported in the literature pertaining to production of nanocarriers encasing peptides and/or proteins, in a way that helps the reader direct a bibliographic search and develop an integrated perspective of the subject. Highlights are given to bioactive proteins and peptides, with a special focus on those from dairy sources (including physicochemical characteristics and properties, and biopharmaceutical application possibilities of e.g. lactoferrin and glycomacropeptide), as well as to nanocarrier functional targeting. Features associated with micro- and (multiple) nanoemulsions, micellar systems, liposomes and solid lipid nanoparticles, together with biopharmaceutical considerations, are presented in the text in a systematic fashion.

Declaration of interest

The authors declare no conflicts of interest.

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