Umbilical artery serum chitotriosidase concentration in pregnancies complicated by preeclampsia and relationship between chitotriosidase levels and fetal blood flow velocity

Abstract

Objective: To evaluate the significance of umbilical cord chitotriosidase concentrations in pregnancies with mild preeclampsia and explore the relationship between fetal chitotriosidase levels and fetal blood flow velocity. Method: The study population included control group (n = 40) and study group with mild preeclampsia (n = 40). Umbilical cord blood samples were collected immediately after delivery. Umbilical artery (UA) flow velocity waveform was determined just before delivery. Results: Umbilical cord chitotriosidase levels and UA S/D rate were significantly high in preeclamptic group. Conclusion: Chitotriosidase may be useful biochemical marker of fetal compromise that reflects the severity of fetoplacental blood flow resistance in pregnancies complicated by preeclampsia.

• Chitotriosidase
• Doppler
• Preeclampsia.

Acknowledgements

We thank Dr. Faruk Balkaya (English Department of Kayseri Erciyes University) for his contribution to English terms and language.

Reference Annotations

The study of Madazli R et al. (chitotriosidase and YKL-40 in normal and preeclamptic pregnancies) may be important. They studied chitotriosidase level in maternal blood and increased levels of chitotriosidase were determined in preeclampsia. Our study illustrated this situation in cord blood.